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三七皂甙联合阿司匹林预防脑梗死复发的临床疗效观察

发布者:zhanglaoshi        发布时间:2019-08-21 13:04:18

三七皂甙联合阿司匹林预防脑梗死复发的临床疗效观察

作者:钟水生王玉周杨慧王世海赵燕华廖华印包泽岩来源:《中国医学创新》2011 年第 32 期

【摘要】 目的观察三七皂甙联合阿司匹林预防脑梗死复发的临床疗效。方法选取本院 2009 年 1 月~2009 年 12 月收治的 76 例脑梗死患者,随机将其分为观察组(使用三七皂甙联合阿司匹林预防治疗)和对照组(单独使用阿司匹林预防治疗)各 38 例,随访 1 年,观察两组的治疗效果,并分析比较。结果观察组中复发 5 例,复发率 13.16%,对照组中复发 8 例,复发率 21.05%,和对照组相比,观察组治疗后血小板聚集率进一步降低,两组治疗效果比较差异有统计学意义(

【关键词】 脑梗死;

三七皂甙;

阿司匹林;

复发

Shui-sheng,WANG Yu-zhou,YANG Hui,WANG Shi-hai,ZHAO Yan-hua,LIAO Hua-yin,BAO Ze-

【Abstract】

Objective To investigate the clinical efficacy of saposins combined with aspirin in preventing ischemic stroke recuurence.Methods 76 patients admitted to our hospital during January 2010 to December 2010 were randomly divided to two groups.Each group have 38 patients.Observation group was treated with saposins and aspirin while the conrtol group with aspirin only.Results There were 5 cases of recurrence in observation group and 8 cases in the control group.The recurence rate was 13.16% and 21.05% seperately,and the difference was significant.Conclusion The effect of saponins combined with aspirin for prevention of recurrence of cerebral infarction was obviously better than that of aspirin,platelet aggregation rate after treatment was further reduced,the follow-up of patients with few recurrences,good preventing effect,it was

【Key words】

Cerebral infarction;

Saposins;

Aspirin;

Recurrence

脑梗死又称缺血性脑卒中,一般由于局部脑组织因血液循环障碍、缺血缺氧而发生的软化坏死。阿司匹林是经典的抗血小板聚集药物,但是尽管部分患者正规治疗,仍不能完全预防缺血性脑梗死的发生。中医药在预防脑梗死中的疗效已经越来越得到肯定。三七皂甙(血塞痛片)又名三七总皂甙,是一种活血祛瘀、通脉活络的中成药,具有抑制血小板聚集和增加脑血流量的作用,对脑血管后遗症和视网膜中央静脉阻塞以及眼前房出血等症状同样具有很好的疗

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